Selank is a synthetic heptapeptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. It is an analogue of the endogenous immunomodulatory peptide tuftsin, to which a Pro-Gly-Pro fragment has been added to enhance its biological stability. In laboratory research settings, Selank is investigated for its complex effects on the central nervous system and its potential interplay with the immune system.

Scientific literature explores Selank’s role in modulating the expression of brain-derived neurotrophic factor (BDNF) and its influence on monoamine neurotransmitter systems, including serotonin. It is frequently utilized in studies examining anxiety-related behaviors, memory consolidation, and the regulation of immune cytokines like interleukins in controlled, non-human experimental models.